Cannabis has historically been stigmatized due to its effects, yet it is now garnering growing acknowledgment for its potential benefits in various medical fields. Recent years have witnessed a significant rise in research focused on the therapeutic properties of cannabis, especially its advantages for neurological conditions.
In addition to its well-known uses for stress relief, reducing depression, and enhancing sleep, cannabis shows promise in tackling a range of neurological disorders. This article explores five such conditions and investigates how a cannabis or cannabis contributes to their therapeutic applications.
Table of Contents
Key Takeaways:
- Specific cannabinoids and terpenes showcase distinct effects on various neurological disorders.
- Linalool, myrcene, and limonene possess anti-convulsant properties.
- Equal ratios of THC and CBD, along with other cannabis compounds, show potential in cancer treatment.
A Natural Approach to Managing Neurological Disorders
Addressing the complexities of conditions like Alzheimer’s disease (AD), brain tumors, Parkinson’s disease (PD), intractable epilepsy, and chronic traumatic encephalopathy (CTE) or traumatic brain injury (TBI) varies based on individual patient requirements and the severity of their condition.
Cannabis is a Viable Treatment Option
Epilepsy
The endocannabinoid system plays a role in influencing the seizure threshold. THC, in particular, has the potential to entirely halt seizures, in contrast to phenobarbital and diphenylhydantoin. Animal studies indicate acute rises in endocannabinoid production and a persistent increase in CB1 production over time. Researchers have noted the anti-convulsant properties of cannabinoids even at non-sedative levels.
THC, THCA, and linalool, a terpenoid found in cannabis, have been subjects of scientific inquiry. The discourse surrounding THCA is intricate, with debates centering on its CB1 activity compared to its spontaneous conversion to THC.
Recent discoveries have also spotlighted the anti-convulsant characteristics of cannabidiolic acid (CBDA), with indications pointing to its serotonergic effects. CBDA displays a notably higher affinity for the 5-HT1A receptor than CBD.
If you are considering exploring cannabis vape pens to aid your condition, seek products containing THC, CBD, THCA, or linalool.
OneStop – THC Distillate Disposable Vape pen Skittlez features linalool as one of its primary terpenes, with THC levels ranging from 16 to 21%.
Brain Tumors
Numerous studies have investigated the application of cannabis in patients diagnosed with brain tumors. A 2006 study published in the British Journal of Cancer revealed that administering THC directly into tumors in patients with glioblastoma multiforme (GBM) slightly prolonged their life expectancy beyond expectations in nine cases.
A case report from the Journal of Child’s Nervous System documented complete regression of residual tumors in two children with pilocytic astrocytomas after smoking cannabis.
THCA, acting as a peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, surpasses CBDA, CBD, or THC in its potential impact. PPARs function as ligand-binding transcription factors, promising to selectively target cancer cells while sparing normal cells. The synergistic effects of THCA alongside other cytotoxic agents emphasize its potential in cancer therapy.
Equal concentrations of THC and CBD, when combined with THCA, CBDA, and cytotoxic terpenoids like limonene, exhibit significant potential in cancer treatment, as suggested by a study in the Planta Medicine Journal. Disposable cannabis pens can encapsulate these cannabinoids and terpenes in a single cartridge.
Parkinson’s Disease
An observational study found that 22 out of 28 participants could tolerate smoked cannabis, presumably THC-dominant. The study highlighted acute benefits, such as enhancements in tremor, rigidity, and bradykinesia among subjects.
In Parkinson’s disease, the loss of cells in the substantia nigra leads to widespread pathology over time. Tau proteins, crucial for the cytoskeleton and axonal transport in neurons, undergo alterations that result in the formation of neurofibrillary tangles.
Nabiximols, a cannabis-based oral spray, significantly reduced tangles when administered to parkin-null mice expressing human tau. This treatment improved dopamine metabolism and glial function while decreasing oxidative stress levels.
THC vape pens like cannabis can be an excellent option for those seeking to improve tremors.
Alzheimer’s Disease
Alzheimer’s disease (AD) is characterized by the formation of senile plaques from β-amyloid (Aβ) proteins, which develop when enzymes cleave a precursor protein (APP). Additionally, neurofibrillary tangles accumulate from tau proteins with excessive phosphate groups attached. At times, these tangles form before the β-amyloid plaques. Once these processes initiate, the disease’s progression remains unyielding.
CBD serves as a protective antioxidant for the brain, safely interacting with NMDA receptors. It combats Alzheimer’s disease by inhibiting the formation of Aβ plaques, mitigating harmful ROS production, and safeguarding fats in PC12 cells exposed to Aβ. CBD also halts tau proteins from acquiring an excess of phosphate groups on PC12 neurons affected by Aβ.
A study involving patients treated with THC-predominant (2.5–30 mg/dose), CBD-predominant, and THCA, primarily administered through tinctures and confections, showed reduced dependency on neuroleptic drugs, alleviated agitation, enhanced appetite, managed aggression, improved sleep quality, boosted mood, decreased demands for nursing care, mitigated self-mutilation tendencies, and controlled pain.
Cannabis components demonstrate potential in addressing various symptoms associated with this complex disorder:
- Agitation may find relief with THC, CBD, and linalool.
- Psychosis symptoms may benefit from CBD.
- THC and linalool may alleviate insomnia and restlessness.
- THC is indicated for anorexia, while THC, CBD, and linalool may assist with aggression.
- THC, limonene, and CBD could potentially help manage depression.
- THC and CBD are known for their pain-relieving properties.
- Alpha-pinene, alongside THC, is linked to memory enhancement.
- CBD and THC are associated with neuroprotection, with THC, CBD, and THCA potentially contributing to reduced Aβ plaque formation.
Traumatic Brain Injury / Chronic Traumatic Encephalopathy
Cannabis, especially chemovars blending THC and CBD, can alleviate symptoms related to CTE, such as headaches, nausea, insomnia, dizziness, agitation, substance abuse, and psychotic symptoms.
A 2019 study indicated that varying concentrations of THC and CBD play a role in alleviating stress, agitation, depression, and anxiety—common emotional responses in cases of chronic traumatic encephalopathy. Cannabinoids assist in reducing glutamate excitotoxicity, a process that leads to nerve cell damage post-traumatic brain injury.
Want to Use cannabis for Your Current Condition?
Engaging in cannabis use is widely accepted as a means to harness its benefits. If you are seeking to mitigate potential health risks associated with traditional methods, cannabis vapes offer a viable alternative.
Ganja Express Canada provides an array of options to help you find the ideal vape pen tailored to your needs. You can select based on the type of pen, including disposable vape pens, whether you prefer Sativa-dominant or Indica-dominant cartridges with high THC, or the specific concentrate it utilizes.
Weed Vape Pens Treat Your Condition
Neurological treatment for the conditions outlined in this article requires considerable advancement. However, innovative approaches such as utilizing cannabis, including through a cannabis pen, in treatment protocols show promise. Research studies and anecdotal evidence suggest that cannabis, with its diverse levels of THC, CBD, and other compounds, can interact with the ECS to help manage symptoms of these conditions.
Frequently Asked Questions
Can a dab pen provide the same experience as a vape pen?
A dab pen and a vape pen both vaporize cannabis concentrates but vary in intensity and usage. Dab pens are designed for solid concentrates like wax and yield a more intense effect. Conversely, vape pens use liquid concentrates, presenting a milder and more controlled experience.
Are THC pens cheap?
The average cost of a cannabis pen is approximately $50, with options ranging from as low as $20 to $200 or more. Price variations depend on battery life and the array of features available.
Can my current medication interact with the active ingredient in my cannabis vape?
This will depend on your prescription drug. For instance, if you take anti-depressants while managing Parkinson’s disease, cannabis may lead to an initial surplus of serotonin, intensifying the body’s reliance on these substances, potentially exacerbating depression and anxiety over time. Consulting your doctor before incorporating cannabis into your current medication regimen is advisable.
Are cannabis pens the best alternative when treating health issues with cannabis?
Weed pens provide a cleaner method to use cannabis without the harmful effects of smoke. This makes them a preferred choice for individuals seeking a less detrimental and more discreet option for managing health issues like pain and anxiety.
However, the appropriateness of cannabis pens can vary based on individual preferences. As research on their long-term effects continues to evolve, it is crucial for anyone considering their use for health reasons to consult with a doctor first to ensure they select the most suitable method for their health requirements.
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